How Effective is this Medication?

There is a growing public awareness that selective publishing biases lead to a distorted and overly optimistic view of the effectiveness of many medications and obscure evidence regarding harmful side effects. A substantial proportion clinical trials evaluating the effectiveness of new medications are funded by pharmaceutical companies. A 2010 study conducted by researchers from both Harvard and Toronto reviewed 500 clinical trials evaluating the effectiveness of five major classes of drugs: antidepressants, ulcer mediation, and so on. They found that 85% of the studies funded by pharmaceutical companies were positive, but only 50% of government funded trials were positive.

In a New York Times article titled Breaking the Drug Seal, journalist Katie Thomas reports on recent initiatives by investigators to find ways of reducing this publication bias.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s